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Intraoperative surgical methods key to AMD treatment
Targeted subretinal surgery for delivery of a novel biosynthetic retinal pigment epithelial (RPE) monolayer in eyes with advanced dry age-related macular degeneration (AMD) has been shown to be feasible using new intraoperative surgical methods, according to Amir H. Kashani, MD, PhD.
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Treating dry eye with recombinant human nerve growth factor
Moderate-to-severe dry eye disease is coming under attack from a new direction. Oxervate (Dompé), a first-in-class recombinant human nerve growth factor (rhNGF) that successfully treats neurotrophic keratitis, is being investigated in a phase IIb trial to see how patients with moderate-to-severe dry eye disease fare with this therapy.
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Gene therapy for LHON: Deciphering phase III data
Phase III studies of a gene therapy for Leber Hereditary Optic Neuropathy have generated some unexpected positive findings. There is biologic plausibility to explain the data.
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